Gordon A Ferns Selected Research

Transforming Growth Factor beta (TGF-beta)

9/2023	Dual targeting of TGF-β and PD-L1 inhibits tumor growth in TGF-β/PD-L1-driven colorectal carcinoma.
1/2023	Therapeutic Potential of Targeting Transforming Growth Factor-beta (TGF-β) and Programmed Death-ligand 1 (PD-L1) in Pancreatic Cancer.
1/2023	Targeting transforming growth factor beta (TGF-β) using Pirfenidone, a potential repurposing therapeutic strategy in colorectal cancer.
1/2022	Association of a genetic variant in Interleukin-10 gene with increased risk and inflammation associated with cervical cancer.
1/2022	Targeting the Transforming Growth Factor-beta Signaling Pathway in the Treatment of Gynecologic Cancer.
1/2021	Inhibition of transforming growth factor-beta by Tranilast reduces tumor growth and ameliorates fibrosis in colorectal cancer.
1/2019	Therapeutic Potential of Targeting Transforming Growth Factor-beta in Colorectal Cancer: Rational and Progress.

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Gordon A Ferns Research Topics

Disease

115	Neoplasms (Cancer) 04/2024 - 09/2016
47	Colorectal Neoplasms (Colorectal Cancer) 04/2024 - 03/2017
42	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/2024 - 12/2011
41	Cardiovascular Diseases (Cardiovascular Disease) 04/2024 - 01/2003
40	Inflammation (Inflammations) 04/2024 - 01/2003
35	Coronary Artery Disease (Coronary Atherosclerosis) 10/2023 - 04/2009
23	Neoplasm Metastasis (Metastasis) 12/2023 - 01/2017
19	Obesity 04/2024 - 01/2013
18	Breast Neoplasms (Breast Cancer) 11/2023 - 01/2017
15	Atherosclerosis 12/2023 - 01/2003
14	Dyslipidemias (Dyslipidemia) 01/2024 - 05/2005
13	Fibrosis (Cirrhosis) 09/2023 - 01/2019
13	Hypertension (High Blood Pressure) 01/2023 - 09/2014
12	Carcinogenesis 01/2024 - 01/2003
12	Diabetes Mellitus 06/2023 - 03/2015
11	Pancreatic Neoplasms (Pancreatic Cancer) 01/2024 - 01/2017
11	Vitamin D Deficiency 02/2022 - 01/2014
10	Premenstrual Syndrome (Premenstrual Tension) 11/2023 - 08/2018
9	Insulin Resistance 01/2024 - 01/2018
9	Dysmenorrhea (Menstrual Pain) 11/2023 - 08/2018
8	Infections 03/2024 - 01/2018
8	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 11/2023 - 01/2019
8	Stroke (Strokes) 06/2021 - 01/2017
7	Non-alcoholic Fatty Liver Disease 01/2024 - 07/2019
7	Uterine Cervical Neoplasms (Cancer of the Cervix) 07/2023 - 12/2017
6	COVID-19 03/2024 - 01/2021
6	Hemorrhage 05/2023 - 10/2018
6	Necrosis 01/2023 - 01/2021
6	Coronary Disease (Coronary Heart Disease) 01/2020 - 02/2011
5	Ovarian Neoplasms (Ovarian Cancer) 03/2024 - 01/2019
5	Body Weight (Weight, Body) 01/2023 - 01/2014
5	Chronic Disease (Chronic Diseases) 11/2021 - 03/2015
5	Colitis 02/2021 - 01/2019
4	Overweight 04/2024 - 01/2017
4	Stomach Neoplasms (Stomach Cancer) 12/2023 - 01/2020
4	Liver Diseases (Liver Disease) 11/2023 - 04/2018
4	Fatty Liver 11/2023 - 01/2019
4	Sleep Initiation and Maintenance Disorders (Insomnia) 11/2023 - 01/2019
4	Disorders of Excessive Somnolence (Hypersomnia) 11/2023 - 01/2020
4	Sleep Wake Disorders 11/2023 - 01/2019
4	Type 2 Diabetes Mellitus (MODY) 10/2023 - 02/2019
4	Pathologic Constriction (Stenosis) 01/2023 - 10/2012

Drug/Important Bio-Agent (IBA)

51	Biomarkers (Surrogate Marker)IBA 01/2024 - 02/2015
32	Vitamin D FDA LinkGeneric 11/2023 - 01/2014
30	AntioxidantsIBA 04/2024 - 01/2003
27	MicroRNAs (MicroRNA)IBA 01/2024 - 01/2016
25	C-Reactive ProteinIBA 04/2024 - 02/2011
24	CytokinesIBA 02/2023 - 01/2002
18	CurcuminIBA 02/2024 - 04/2017
18	Proteins (Proteins, Gene)FDA Link 10/2023 - 02/2011
17	Triglycerides (Triacylglycerol)IBA 04/2024 - 03/2015
17	ZincIBA 03/2024 - 01/2012
16	CholesterolIBA 10/2023 - 07/2016
15	LipidsIBA 02/2024 - 01/2015
14	Fluorouracil (Carac)FDA LinkGeneric 09/2023 - 01/2017
13	EnzymesIBA 08/2023 - 01/2016
12	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2024 - 02/2011
12	HDL CholesterolIBA 04/2024 - 03/2015
12	CopperIBA 12/2023 - 01/2012
10	oxidized low density lipoproteinIBA 01/2024 - 10/2012
10	Blood Glucose (Blood Sugar)IBA 12/2023 - 03/2015
10	HSP27 Heat-Shock ProteinsIBA 01/2023 - 05/2011
9	CalciumIBA 03/2024 - 01/2018
9	CateninsIBA 07/2023 - 01/2019
9	Angiotensin Receptor AntagonistsIBA 08/2022 - 01/2020
8	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2023 - 09/2014
8	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2022 - 01/2018
7	Uric Acid (Urate)IBA 04/2024 - 01/2018
7	Transforming Growth Factor beta (TGF-beta)IBA 09/2023 - 01/2019
7	Interleukin-6 (Interleukin 6)IBA 09/2023 - 06/2015
7	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2020 - 01/2017
6	Glucose (Dextrose)FDA LinkGeneric 01/2024 - 07/2019
6	Long Noncoding RNAIBA 01/2024 - 11/2018
6	RNA (Ribonucleic Acid)IBA 12/2023 - 01/2019
6	DNA (Deoxyribonucleic Acid)IBA 11/2023 - 01/2017
5	Insulin (Novolin)FDA Link 01/2024 - 03/2016
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2024 - 01/2016
5	VitaminsIBA 07/2023 - 10/2018
5	AntigensIBA 03/2023 - 08/2017
5	CollagenIBA 01/2023 - 01/2019
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 11/2017
5	Cadherins (E-Cadherin)IBA 01/2023 - 01/2019
5	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2023 - 01/2018
5	Angiotensin IIIBA 01/2022 - 01/2018
5	HDL LipoproteinsIBA 11/2021 - 03/2015
5	Vitamin E FDA LinkGeneric 01/2021 - 04/2017
5	Trace Elements (Biometals)IBA 02/2019 - 01/2012
4	IronIBA 03/2024 - 09/2020
4	AdipokinesIBA 10/2023 - 03/2016
4	Phosphorus (Red Phosphorus)IBA 07/2023 - 11/2017
4	LDL Lipoproteins (beta Lipoproteins)IBA 06/2023 - 10/2012
4	Antihypertensive Agents (Antihypertensives)IBA 01/2023 - 01/2018
4	Therapeutic UsesIBA 01/2023 - 01/2019
4	Transforming Growth Factors (Transforming Growth Factor)IBA 12/2022 - 01/2019
4	AngiotensinsIBA 08/2022 - 01/2022

Therapy/Procedure

52	Therapeutics 04/2024 - 03/2016
17	Drug Therapy (Chemotherapy) 01/2024 - 01/2018
6	Immunotherapy 01/2024 - 01/2018
5	Stents 02/2023 - 02/2011
4	Radiotherapy 01/2023 - 03/2018